实验室近期在本领域发表论文50余篇，其中SCI收录论文49篇：

1.Zhu-Ping Xiao,* Wei Wei,Qi Liu, Peng-Fei Wang, Xing Luo, Fang-Yuan Chen, Yang Cao, Hong-Xia Huang,Mi-Mi Liu and Hai-Liang Zhu, C-7 modified flavonoids as novel tyrosyl-tRNAsynthetase inhibitors. RSC Advances2017, 7, 6193–6201.

2.Wei Wei, Qi Liu, Zhen-ZhenLi, Wei-Kang Shi, Xing Fu, Jia Liu, Xuan Zhu, Xiao-Cong Wang, Ning Xu, Teng-FeiLi, Fu-Rui Jiang, Zhu-Ping Xiao* and Hai-Liang Zhu*, Synthesis and evaluationof adenosine containing 3-arylfuran-2(5H)-ones as tyrosyl-tRNAsynthetase inhibitors. Eur. J. Med. Chem. 2017, 133,62-68.

3.Wang, G.; Peng, Z.; Wang,J.; Li, X.; Li, J., Synthesis, in vitro evaluation and molecular dockingstudies of novel triazine-triazole derivatives as potential α-glucosidaseinhibitors. Eur. J. Med. Chem. 2017, 125, 423-429.

4.Wang, G.; Li, X.; Wang,J.; Xie, Z.; Li, L.; Chen, M.; Chen, S.; Peng, Y., Synthesis, molecular dockingand α-glucosidase inhibition of2-((5,6-diphenyl-1,2,4-triazin-3-yl)thio)-N-arylacetamides. Bioorg. Med.Chem. Lett. 2017, 27 (5), 1115-1118.

5.Ouyang, H.*, Hou, K.,Wang, L., Peng, W., Optimization Protocol for the Microwave-Assisted Extractionof Antioxidant Components from Pinus elliottii Needles Using Response SurfaceMethodology. BioResources, 12, 2017. 478-494.

6.ShiTang*, Li Yuan, You-Lin Deng, Zeng-Zeng Li, Liang-Neng Wang, Gui-Xiu Huang,Rui-Long Sheng*, Visible-light-induced perfluoroalkylation/arylmigr- ation/desulfonylationcascades of conjugated tosyl amides. Tetrahedron Letters2017, 58,329–332.

7.Yu-Yang Xie^#,Ying-Chun Wang^#, Yan-He, Da-Chao Hu, Ying-Ming Pan*, and Heng-ShanWang*, Catalyst-free synthesis of fused 1,2,3-triazole and isoindolinederivatives via an intramolecular azide–alkene cascade, Green Chemistry,GreenChemistry2017, 19, 656–659.

8.Wei-Kang Shi, Rui-ChengDeng, Peng-Fei Wang, Qin-Qin Yue, Qi Liu, Kun-Ling Ding, Mei-Hui Yang, Hong-YuZhang, Si-Hua Gong, Min Deng, Wen-Run Liu, Qiu-Ju Feng, Zhu-Ping Xiao,*Hai-Liang Zhu, 3-Arylpropionylhydroxamic acid derivatives as Helicobacterpylori urease inhibitors: Synthesis, molecular docking and biologicalevaluation. Bioorg. Med. Chem.2016, 24, 4519–4527.

9.Wang, G.; Peng, Z.; Wang,J.; Li, J.; Li, X., Synthesis, biological evaluation and molecular dockingstudy of N-arylbenzo[d]oxazol-2-amines as potential α-glucosidase inhibitors. Bioorg.Med. Chem. 2016, 24 (21), 5374-5379.

10.Wang, G.; Wang, J.; He, D.; Li, X.;Li, J.; Peng, Z., Synthesis and biological evaluation of novel 1,2,4-triazinederivatives bearing carbazole moiety as potent α-glucosidase inhibitors. Bioorg.Med. Chem. Lett. 2016, 26 (12), 2806-2809.

11.Xiang Q, Yu C, Zhu Y F, Li CY, Tian RB, Li XH*, Nuclear factorerythroid 2-related factor 2 antibody attenuates thermal hyperalgesia in thedorsal root ganglion: Neurochemical changes and behavioral studies aftersciatic nerve-pinch injury. Injury.2016, 47(8), 1647-1654.

12.ShiTang,* You-Lin Deng, Jie Li, Wen-Xin Wang, Ying-Chun Wang, Zeng-Zeng Li, LiYuan, Shi-Lu Chen*, Rui-Long Sheng, Aerobic oxidative cyclization of benzamidesvia meta-selective C–H tert-alkylation: rapid entry to 7-alkylatedisoquinolinediones. Chem. Commun.2016, 52, 4170-4173.

13.You-LinDeng, Shi Tang,* Guo-Liang Ding, Ming-Wei Wang, Jie Li, Zeng-Zeng Li, Li Yuanand Rui-Long Sheng, Radical-mediated divergent cyclization of benzamides towardperfluorinated or cyanated isoquinolinediones, Org. Biomol. Chem. 2016,14, 9348-9353.

14.Yan He^#, Ying-chun Wang^#,Kun Hu, Xiao-ling Xu, Heng-Shan Wang*, and Ying-Ming Pan*, Palladium-CatalyzedSynthesis of 5‑Iminopyrrolones throughIsocyanide Double Insertion Reaction with Terminal Alkynes and Water, TheJournal of Organic Chemistry2016, 81, 11813−11818.

15.Wei Wei, Wei-Kang Shi, Peng-Fei Wang,Xiao-Tong Zeng, Pan Li, Ji-Rong Zhang, Qian Li, Zhi-Ping Tang, Jia Peng,Lang-Zhou Wu, Mei-Qun Xie, Chan Liu, Xian-Hui Li, Ying-Chun Wang, Zhu-PingXiao*, and Hai-Liang Zhu, Adenosine analogues as inhibitors of tyrosyl-tRNAsynthetase: design, synthesis and antibacterial evaluation. Bioorg. Med.Chem.2015, 23, 6602–6611.

16.Zhu-Ping Xiao*, Wei Wei, Peng-FeiWang, Wei-Kang Shi, Na Zhu, Me-Qun Xie, Yu-Wen Sun, Ling-Xia Li, Yong-XiangXie, Liang-Song Zhu, Nian Tang, Hui Ouyang, Xian-Hui Li, Guang-Cheng Wang andHai-Liang Zhu, Synthesis and Evaluation of New Tyrosyl-tRNA SynthetaseInhibitors as Antibacterial Agents Based on a N2-(arylacetyl)glycinanilideScaffold. Eur. J. Med. Chem. 2015, 102, 631-638.

17.Zhu-Ping Xiao*, Wei-Kang Shi,Peng-Fei Wang, Wei Wei, Xiao-Tong Zeng, Ji-Rong Zhang, Na Zhu, Miao Peng, BinPeng, Xiao-Yi Lin, Hui Ouyang, Xiao-Chun Peng, Guang-Cheng Wang and Hai-LiangZhu, Synthesis and evaluation of N-analogues of 1,2-diarylethane as Helicobacterpylori urease inhibitors. Bioorg. Med. Chem.2015, 23(15),4508-4513.

18.Xu-Dong Wang, Wei Wei, Peng-Fei Wang,Li-Cheng Yi, Wei-Kang Shi, Yong-Xiang Xie, Lang-Zhou Wu, Nian Tang, Liang-SongZhu, Jia Peng, Chan Liu, Xian-Hui Li, Shi Tang, Zhu-Ping Xiao*, and Hai-LiangZhu, Synthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-onesas anti-gastric ulcer agent. Bioorg. Med. Chem.2015, 23,4860–4865.

19.Yao-FengZhu , Xian-Hui Li*,Zhi-PengYuan , Chun-YanLi , Rong-BoTian , WeiJia , Zhu-Ping Xiao, Allicinimprovesendoplasmic reticulum stress-related cognitivedeficits. European Journal ofPharmacology.2015,762, 239-46.  

20.QiongXiang , Jie Zhang , Chun-Yan Li , YanWang , Mao-Jun Zeng , Zhi-Xin Cai ,Rong-Bo Tian a,Wei Jia , Xian-Hui Li*, Insulin resistance-induced hyperglycemiadecreased the activation of Akt/CREB in hippocampus neurons: Molecular evidencefor mechanism of diabetes-induced cognitive dysfunction. Neuropeptides2015, 54(12), 9-15.

21.Shi Tang*, Shu-Hua Li , Zhi-Hao Li ,Dong Zhou, Rui-Long Sheng*, DIAD as a promoter for cyanomethylation of alkenesby Cu catalysis. Tetrahedron Lett. 2015, 56,1423–1426

22.Shi Tang,* You-Lin Deng, Jie Li,Wen-Xin Wang, Guo-Liang Ding, Ming-Wei Wang, Zhu-Ping Xiao, Ying-Chun Wang, andRui-Long Sheng, Synthesis of Perfluorinated Isoquinolinediones throughVisible-Light-Induced Cyclization of Alkenes. J. Org. Chem.2015,80, 12599−12605.

23.Shi Tang*, Dong Zhou, Zhi-Hao Lia,Mei-Jun Fu, Jie Li, Rui-Long Sheng*, Shu-Hua Lia, Azo-Compound-MediatedCyanoalkylation of Alkenes by Copper Catalysis: General Access toCyano-Substituted Oxindoles. Synthesis2015, 47, 1567–1580

24.Shi Tang,* Zhi-Hao Li, Ming-Wei Wang,Zhi-Ping Li and Rui-Long Sheng, Metal-free cascade cyclization of alkenestoward perfluorinated oxindoles Org. Biomol. Chem.2015, 13,5285-5288.

25.Shi Tang1*, Dong Zhou, Youlin Deng,Zhihao Li, You Yang, Jianguang He & Yingchun Wang, Copper-catalyzedMeerwein carboarylation of alkenes with anilines to form3-benzyl-3-alkyloxindole,  Sci China Chem. 2015, 58,684–688.

26.Dong Zhou, Zi-Hao Li, Jie Li, Shu-HuaLi, Ming-Wei Wang, Xiao-Ling Luo, Guo-Liang Ding, Rui-Long Sheng,* Mei-Jun Fu,and Shi Tang*, Copper-Catalysed Alkylarylation of Activated Alkenes Using AIBNand Beyond: An Access to Cyano-Containing Oxindoles, Eur. J. Org. Chem. 2015,1606–1612

27.Yingchun Wang, Jiuling Li, Yan He,Yuyang Xie, Hengshan Wang*, and Yingming Pan*, Synthesis of PolysubstitutedImidazoles and Pyridines via Samarium(III) Triflate-Catalyzed [2 + 2 + 1] and[4 + 2] Annulations of Unactivated Aromatic Alkenes with Azides, AdvancedSynthesis＆Catalysis2015, 357, 3229 –3241.

28.Jiu-ling Li^#, Ying-chunWang^#, Wei-ze Li, Heng-shan Wang*, Dong-liang Mo and Ying-ming Pan*,Facile synthesis of 2,5-disubstituted oxazoles via a copper-catalyzed cascadereaction of alkenes with azides. Chemical Communications2015, 51,17772–17774.

29.Ying-chun Wang, Yu-yang Xie,Xian-chun Tan, Heng-shan Wang* and Ying-ming Pan*, Sc(OTf)3-mediated1,3-dipolar cycloaddition–ringcleavage–rearrangement: a highly stereoselectiveaccess to Z-β-enaminonitriles, Organic & Biomolecular Chemistry2015, 13, 513–519.

30.Xu-Dong Wang, Wei Wei, Peng-Fei Wang,Yun-Tao Tang, Rui-Cheng Deng, Biao Li, Sha-Sha Zhou, Jing-Wen Zhang, Lei Zhang,Zhu-Ping Xiao*, Hui Ouyang, and Hai-Liang Zhu, Novel 3-Arylfuran-2(5H)-one-FluoroquinoloneHybrid: design, synthesis and evaluation as antibacterial agent. Bioorg.Med. Chem.2014, 22, 3620-3628.

31.Zhu-Ping Xiao*, Xu-Dong Wang,Peng-Fei Wang, Yin Zhou, Jing-Wen Zhang, Lei Zhang, Jiao Zhou, Sha-Sha Zhou,Hui Ouyang, Xiao-Yi Lin, Manzira Mustapa, Asaimuguli Reyinbaike, and Hai-LiangZhua*, Design, Synthesis, and Evaluation of Novel Fluoroquinolone-FlavonoidHybrids as Potent Antibiotics against Drug-Resistant Microorganisms. Eur. J.Med. Chem. 2014, 80, 92-100.

32.Wang, G.; Wang, F.; Cao, D.; Liu, Y.;Zhang, R.; Ye, H.; Li, X.; He, L.; Yang, Z.; Ma, L.; Peng, A.; Xiang, M.; Wei,Y.; Chen, L., Synthesis, structure–activity relationships and biologicalevaluation of barbigerone analogues as anti-proliferative and anti-angiogenesisagents. Bioorg. Med. Chem. Lett. 2014, 24 (14), 3158-3163.

33.Wang, G.; Li, C.; He, L.; Lei, K.;Wang, F.; Pu, Y.; Yang, Z.; Cao, D.; Ma, L.; Chen, J.; Sang, Y.; Liang, X.;Xiang, M.; Peng, A.; Wei, Y.; Chen, L., Design, Synthesis and BiologicalEvaluation of a Series of Pyrano Chalcone Derivatives Containing Indole Moietyas Novel Anti-tubulin Agents. Bioorg. Med. Chem. 2014, 22(7), 2060–2079.

34.Ouyang H*, Yu J, Chang J, Deng H,Separation characteristics and component comparison of woody extracts ofIllicium verum fruit. Pak J Pharm Sci.2014, 27, 2067-71.

35.Xu-Dong Wang, Wei Wei, Peng-Fei Wang,Yun-Tao Tang, Rui-Cheng Deng, Biao Li, Sha-Sha Zhou, Jing-Wen Zhang, Lei Zhang,Zhu-Ping Xiao*, Hui Ouyang*, Hai-Liang Zhu*, Novel3-arylfuran-2(5H)-one-fluoroquinolone hybrid: Design, synthesis and evaluationas antibacterial agent, Bioorganic & Medicinal Chemistry 2014,22(14), 3620-3628.

36.Shi Tang,* Dong Zhou, and Ying-ChunWang*, Metal-Free Meerwein Carboarylation of Alkenes with Anilines: AStraightforward Approach to 3-Benzyl-3-alkyloxindoles. Eur. J. Org. Chem.2014, 3656–3661.

37.Qing-lanLi, Shi Tang, Dong Zhou & Xin-mei Tang, A Simple Preparation Process of syn-Phenylpropanolaminesfrom Racemic OTBDPS Cyanohydrins, Synthetic Commun.2014, 44,1600-1607.

38.Ying-Chun Wang^#, Yu-YangXie^#, Hong-En Qu, Heng-Shan Wang*, Ying-Ming Pan*, and Fu-PingHuang, Ce(OTf)3-Catalyzed [3 + 2] Cycloaddition of Azides with Nitroolefins:Regioselective Synthesis of 1,5-Disubstituted 1,2,3-Triazoles, The Journalof Organic Chemistry2014, 79, 4463−4469.

39.Yu-Yang Xie^#, Ying-ChunWang^#, Hong-En Qu, Xian-Chun Tan, Heng-Shan Wang*, and Ying-MingPan*, Regioselective Synthesis of β-Aryl Enaminones and 1,4,5-Trisubstituted 1,2,3-Triazolesfrom Chalcones and Benzyl Azides, Advanced Snythesis＆Catalysis2014, 356,3347–3355.

40.Shi Tang,* Dong Zhou, and Ying-ChunWang*, Metal-Free Meerwein Carboarylation of Alkenes with Anilines: AStraightforward Approach to 3-Benzyl-3-alkyloxindoles. European Journal ofOrganic Chemistry2014, 3656–3661.

41.Ying-Chun Wang, Heng-Shan Wang*,Guo-Bao Huang, Fu-Ping Huang, Kun Hu, Ying-Ming Pan*, A one-pot approach to4,5-dihydropyrazoles from ketones, arylacetylenes, and hydrazines, Tetrahedron2014, 70, 1621–1628.

42.Zhu-Ping Xiao*, Zhi-Yun Peng, Jing-JunDong, Juan He, Hui Ouyang, Yu-Ting Feng, Chun-Lei Lu, Wan-Qiang Lin, Jin-XiangWang, Yin-Ping Xiang and Hai-Liang Zhu*, Synthesis, structure-activityrelationship analysis and kinetics study of reductive derivatives of flavonoidsas Helicobacter pylori urease inhibitors. Eur. J. Med. Chem. 2013,63, 685-695.

43.Xu-Dong Wang, Rui-ChengDeng, Jing-Jun Dong, Zhi-YunPeng, Xiao-Ming Gao, Shu-TingLi, Wan-Qiang Lin, Chun-LeiLu, Zhu-Ping Xiao* and Hai-Liang Zhu*, 3-Aryl-4-acyloxyethoxyfuran-2(5H)-ones asinhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking andantibacterial evaluation. Bioorg. Med. Chem.2013, 21,4914-4922.

44.Zhu-Ping Xiao*, Zhi-Yun Peng, Jing-Jun Dong,Rui-Cheng Deng, Xu-Dong Wang, Hui Ouyang, Pan Yang, Juan He, Yuan-Feng Wang,Man Zhu, Xiao-Chun Peng, Wan-Xi Peng and Hai-Liang Zhu, Synthesis, moleculardocking and kinetic properties of β-hydroxy-β-phenylpropionyl-hydroxamicacids as Helicobacter pylori urease inhibitors. Eur. J. Med. Chem.2013, 68, 212-221.

45.Wang, G.; Peng, F.; Cao, D.; Yang,Z.; Han, X.; Liu, J.; Wu, W.; He, L.; Ma, L.; Chen, J.; Sang, Y.; Xiang, M.;Peng, A.; Wei, Y.; Chen, L., Design, synthesis and biological evaluation ofmillepachine derivatives as a new class of tubulin polymerization inhibitors. Bioorg.Med. Chem. 2013, 21 (21), 6844-6854.

46.Xian-Hui Li, Xin Xin, Yan Wang, Jian-zhaoWu, Pentamethylquercetin ameliorates cognitive deficits  through enhancingAkt/CREB signaling pathways activity in diabeticGoto-Kakizaki Rats.J Alzheimers Dis. 2013, 34(3),755-67.

47.H. Ouyang*, J. Yu, Study on AucutinExtraction in Eucommia Key Fruit Seeds Meal by Supercritical CO₂Mixed with Entrainers, Advanced Materials Research2013, 610-613,3545-3548.

48.Tang Shi*, Li Shu Hua, Zhou Dong,Zeng Hui Qiong & Wang Nai Xing, Stereoselective C(sp3)-C(sp2) Negishicoupling of (2-amido-1-phenylpropyl)zinc compounds through the steric controlof  β-amido group. Sci. China Chem. 2013, 56,1293–1300.

49.Tang Shi*, Zhou Dong, Li Shu-Hua AndWang Nai-Xing, Stereoselective Palladium-catalyzed Cross-coupling of(2-Amido-1-phenylpropyl)zinc Compounds with Aryl Bromides. Chem. Res. Chin.Univ.2013, 29, 678-681.

Wang, Zhu-Ping Xiao,Ying-Chun Wang, and Rui-Long Sheng, Synthesis of PerfluorinatedIsoquinolinediones through Visible-Light-Induced Cyclization of Alkenes. J.Org. Chem.2015, 80, 12599−12605.

23.Shi Tang*, Dong Zhou, Zhi-Hao Lia,Mei-Jun Fu, Jie Li, Rui-Long Sheng*, Shu-Hua Lia, Azo-Compound-MediatedCyanoalkylation of Alkenes by Copper Catalysis: General Access toCyano-Substituted Oxindoles. Synthesis2015, 47, 1567–1580

24.Shi Tang,* Zhi-Hao Li, Ming-Wei Wang,Zhi-Ping Li and Rui-Long Sheng, Metal-free cascade cyclization of alkenestoward perfluorinated oxindoles Org. Biomol. Chem.2015, 13,5285-5288.

25.Shi Tang1*, Dong Zhou, Youlin Deng,Zhihao Li, You Yang, Jianguang He & Yingchun Wang, Copper-catalyzedMeerwein carboarylation of alkenes with anilines to form3-benzyl-3-alkyloxindole,  Sci China Chem. 2015, 58,684–688.

26.Dong Zhou, Zi-Hao Li, Jie Li, Shu-HuaLi, Ming-Wei Wang, Xiao-Ling Luo, Guo-Liang Ding, Rui-Long Sheng,* Mei-Jun Fu,and Shi Tang*, Copper-Catalysed Alkylarylation of Activated Alkenes Using AIBNand Beyond: An Access to Cyano-Containing Oxindoles, Eur. J. Org. Chem. 2015,1606–1612

27.Yingchun Wang, Jiuling Li, Yan He,Yuyang Xie, Hengshan Wang*, and Yingming Pan*, Synthesis of PolysubstitutedImidazoles and Pyridines via Samarium(III) Triflate-Catalyzed [2 + 2 + 1] and[4 + 2] Annulations of Unactivated Aromatic Alkenes with Azides, AdvancedSynthesis＆Catalysis2015, 357, 3229 –3241.

28.Jiu-ling Li^#, Ying-chunWang^#, Wei-ze Li, Heng-shan Wang*, Dong-liang Mo and Ying-ming Pan*,Facile synthesis of 2,5-disubstituted oxazoles via a copper-catalyzed cascadereaction of alkenes with azides. Chemical Communications2015, 51,17772–17774.

29.Ying-chun Wang, Yu-yang Xie,Xian-chun Tan, Heng-shan Wang* and Ying-ming Pan*, Sc(OTf)3-mediated1,3-dipolar cycloaddition–ringcleavage–rearrangement: a highly stereoselectiveaccess to Z-β-enaminonitriles, Organic & Biomolecular Chemistry2015, 13, 513–519.